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PRC2 and EHMT1 regulate H3K27me2 and H3K27me3 establishment across the zygote genome
The formation of zygote is the beginning of mammalian life, and dynamic epigenetic modifications are essential for mammalian normal development. H3K27 di-methylation (H3K27me2) and H3K27 tri-methylation (H3K27me3) are marks of facultative heterochromatin which maintains transcriptional repression es...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733509/ https://www.ncbi.nlm.nih.gov/pubmed/33311485 http://dx.doi.org/10.1038/s41467-020-20242-9 |