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Intravenous injection of the oncolytic virus M1 awakens antitumor T cells and overcomes resistance to checkpoint blockade

Reversing the highly immunosuppressive tumor microenvironment (TME) is essential to achieve long-term efficacy with cancer immunotherapy. Despite the impressive clinical response to checkpoint blockade in multiple types of cancer, only a minority of patients benefit from this approach. Here, we repo...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Cai, Jing, Liu, Wenfeng, Lin, Yuan, Guo, Li, Liu, Xincheng, Qin, Zhen, Xu, Cuiying, Zhang, Yanming, Su, Xingwen, Deng, Kai, Yan, Guangmei, Liang, Jiankai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733593/
https://www.ncbi.nlm.nih.gov/pubmed/33311488
http://dx.doi.org/10.1038/s41419-020-03285-0