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Intravenous injection of the oncolytic virus M1 awakens antitumor T cells and overcomes resistance to checkpoint blockade
Reversing the highly immunosuppressive tumor microenvironment (TME) is essential to achieve long-term efficacy with cancer immunotherapy. Despite the impressive clinical response to checkpoint blockade in multiple types of cancer, only a minority of patients benefit from this approach. Here, we repo...
Autores principales: | Liu, Yang, Cai, Jing, Liu, Wenfeng, Lin, Yuan, Guo, Li, Liu, Xincheng, Qin, Zhen, Xu, Cuiying, Zhang, Yanming, Su, Xingwen, Deng, Kai, Yan, Guangmei, Liang, Jiankai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733593/ https://www.ncbi.nlm.nih.gov/pubmed/33311488 http://dx.doi.org/10.1038/s41419-020-03285-0 |
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