Human iNSC-derived brain organoid model of lysosomal storage disorder in Niemann–Pick disease type C

Recent studies on developing three-dimensional (3D) brain organoids from stem cells have allowed the generation of in vitro models of neural disease and have enabled the screening of drugs because these organoids mimic the complexity of neural tissue. Niemann-Pick disease, type C (NPC) is a neurodeg...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Seung-Eun, Shin, Nari, Kook, Myung Geun, Kong, Dasom, Kim, Nam Gyo, Choi, Soon Won, Kang, Kyung-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733597/
https://www.ncbi.nlm.nih.gov/pubmed/33311479
http://dx.doi.org/10.1038/s41419-020-03262-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733597/
https://www.ncbi.nlm.nih.gov/pubmed/33311479
http://dx.doi.org/10.1038/s41419-020-03262-7

Ejemplares similares