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High-fat diet-fed ovariectomized mice are susceptible to accelerated subcutaneous tumor growth potentially through adipose tissue inflammation, local insulin-like growth factor release, and tumor associated macrophages

Background: The association between obesity and colorectal cancer (CRC) risk has been well established. This relationship appears to be more significant in men than in women, which may be attributable to sex hormones. However, controlled animal studies to substantiate these claims and the mechanisms...

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Detalles Bibliográficos
Autores principales: Bader, Jackie, Carson, Meredith, Enos, Reilly, Velazquez, Kandy, Sougiannis, Alexander, Singh, Udai, Becker, William, Nagarkatti, Mitzi, Fan, Daping, Murphy, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733624/
https://www.ncbi.nlm.nih.gov/pubmed/33346251
http://dx.doi.org/10.18632/oncotarget.27832