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High-fat diet-fed ovariectomized mice are susceptible to accelerated subcutaneous tumor growth potentially through adipose tissue inflammation, local insulin-like growth factor release, and tumor associated macrophages
Background: The association between obesity and colorectal cancer (CRC) risk has been well established. This relationship appears to be more significant in men than in women, which may be attributable to sex hormones. However, controlled animal studies to substantiate these claims and the mechanisms...
Autores principales: | Bader, Jackie, Carson, Meredith, Enos, Reilly, Velazquez, Kandy, Sougiannis, Alexander, Singh, Udai, Becker, William, Nagarkatti, Mitzi, Fan, Daping, Murphy, Angela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733624/ https://www.ncbi.nlm.nih.gov/pubmed/33346251 http://dx.doi.org/10.18632/oncotarget.27832 |
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