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Coordination of transcription, processing, and export of highly expressed RNAs by distinct biomolecular condensates

Genes under control of super-enhancers are expressed at extremely high levels and are frequently associated with nuclear speckles. Recent data suggest that the high concentration of unphosphorylated RNA polymerase II (Pol II) and Mediator recruited to super-enhancers create phase-separated condensat...

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Detalles Bibliográficos
Autores principales: Ishov, Alexander M., Gurumurthy, Aishwarya, Bungert, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733674/
https://www.ncbi.nlm.nih.gov/pubmed/32338276
http://dx.doi.org/10.1042/ETLS20190160