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Renal deposits of complement factors as predictors of end-stage renal disease and death in patients with lupus nephritis

OBJECTIVE: Lupus nephritis (LN) increases the risks of end-stage renal disease (ESRD) and death, but these risks are difficult to estimate. Since complement factors play an essential role in the pathogenesis and are deposited in the kidneys as C1q and C3, we studied whether these deposits predict ES...

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Detalles Bibliográficos
Autores principales: Koopman, Jacob J E, Rennke, Helmut G, Leatherwood, Cianna, Speyer, Cameron B, D’Silva, Kristin, McMahon, Gearoid M, Waikar, Sushrut S, Costenbader, Karen H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733722/
https://www.ncbi.nlm.nih.gov/pubmed/32413140
http://dx.doi.org/10.1093/rheumatology/keaa174