Decreased mechanotransduction prevents nuclear collapse in a Caenorhabditis elegans laminopathy

The function of the nucleus depends on the integrity of the nuclear lamina, an intermediate filament network associated with the linker of nucleoskeleton and cytoskeleton (LINC) complex. The LINC complex spans the nuclear envelope and mediates nuclear mechanotransduction, the process by which mechan...

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Detalles Bibliográficos
Autores principales: Huelgas-Morales, Gabriela, Sanders, Mark, Mekonnen, Gemechu, Tsukamoto, Tatsuya, Greenstein, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733798/
https://www.ncbi.nlm.nih.gov/pubmed/33229589
http://dx.doi.org/10.1073/pnas.2015050117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733798/
https://www.ncbi.nlm.nih.gov/pubmed/33229589
http://dx.doi.org/10.1073/pnas.2015050117

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