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Decreased mechanotransduction prevents nuclear collapse in a Caenorhabditis elegans laminopathy
The function of the nucleus depends on the integrity of the nuclear lamina, an intermediate filament network associated with the linker of nucleoskeleton and cytoskeleton (LINC) complex. The LINC complex spans the nuclear envelope and mediates nuclear mechanotransduction, the process by which mechan...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733798/ https://www.ncbi.nlm.nih.gov/pubmed/33229589 http://dx.doi.org/10.1073/pnas.2015050117 |