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Functional redundancy of type I and type II receptors in the regulation of skeletal muscle growth by myostatin and activin A

Myostatin (MSTN) is a transforming growth factor-β (TGF-β) family member that normally acts to limit muscle growth. The function of MSTN is partially redundant with that of another TGF-β family member, activin A. MSTN and activin A are capable of signaling through a complex of type II and type I rec...

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Detalles Bibliográficos
Autores principales: Lee, Se-Jin, Lehar, Adam, Liu, Yewei, Ly, Chi Hai, Pham, Quynh-Mai, Michaud, Michael, Rydzik, Renata, Youngstrom, Daniel W., Shen, Michael M., Kaartinen, Vesa, Germain-Lee, Emily L., Rando, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733802/
https://www.ncbi.nlm.nih.gov/pubmed/33219121
http://dx.doi.org/10.1073/pnas.2019263117