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Functional redundancy of type I and type II receptors in the regulation of skeletal muscle growth by myostatin and activin A
Myostatin (MSTN) is a transforming growth factor-β (TGF-β) family member that normally acts to limit muscle growth. The function of MSTN is partially redundant with that of another TGF-β family member, activin A. MSTN and activin A are capable of signaling through a complex of type II and type I rec...
Autores principales: | Lee, Se-Jin, Lehar, Adam, Liu, Yewei, Ly, Chi Hai, Pham, Quynh-Mai, Michaud, Michael, Rydzik, Renata, Youngstrom, Daniel W., Shen, Michael M., Kaartinen, Vesa, Germain-Lee, Emily L., Rando, Thomas A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733802/ https://www.ncbi.nlm.nih.gov/pubmed/33219121 http://dx.doi.org/10.1073/pnas.2019263117 |
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