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The SERCA residue Glu340 mediates interdomain communication that guides Ca(2+) transport

The sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA) is a P-type ATPase that transports Ca(2+) from the cytosol into the sarco(endo)plasmic reticulum (SR/ER) lumen, driven by ATP. This primary transport activity depends on tight coupling between movements of the transmembrane helices forming the t...

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Detalles Bibliográficos
Autores principales: Geurts, Maxwell M. G., Clausen, Johannes D., Arnou, Bertrand, Montigny, Cédric, Lenoir, Guillaume, Corey, Robin A., Jaxel, Christine, Møller, Jesper V., Nissen, Poul, Andersen, Jens Peter, le Maire, Marc, Bublitz, Maike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733806/
https://www.ncbi.nlm.nih.gov/pubmed/33229570
http://dx.doi.org/10.1073/pnas.2014896117