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Chromatin topology and the timing of enhancer function at the HoxD locus
The HoxD gene cluster is critical for proper limb formation in tetrapods. In the emerging limb buds, different subgroups of Hoxd genes respond first to a proximal regulatory signal, then to a distal signal that organizes digits. These two regulations are exclusive from one another and emanate from t...
Autores principales: | Rodríguez-Carballo, Eddie, Lopez-Delisle, Lucille, Willemin, Andréa, Beccari, Leonardo, Gitto, Sandra, Mascrez, Bénédicte, Duboule, Denis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733857/ https://www.ncbi.nlm.nih.gov/pubmed/33229569 http://dx.doi.org/10.1073/pnas.2015083117 |
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