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Syndecan-1 Promotes Streptococcus pneumoniae Corneal Infection by Facilitating the Assembly of Adhesive Fibronectin Fibrils

Subversion of heparan sulfate proteoglycans (HSPGs) is thought to be a common virulence mechanism shared by many microbial pathogens. The prevailing assumption is that pathogens co-opt HSPGs as cell surface attachment receptors or as inhibitors of innate host defense. However, there are few data tha...

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Detalles Bibliográficos
Autores principales: Jinno, Akiko, Hayashida, Atsuko, Jenkinson, Howard F., Park, Pyong Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733941/
https://www.ncbi.nlm.nih.gov/pubmed/33293379
http://dx.doi.org/10.1128/mBio.01907-20