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Syndecan-1 Promotes Streptococcus pneumoniae Corneal Infection by Facilitating the Assembly of Adhesive Fibronectin Fibrils
Subversion of heparan sulfate proteoglycans (HSPGs) is thought to be a common virulence mechanism shared by many microbial pathogens. The prevailing assumption is that pathogens co-opt HSPGs as cell surface attachment receptors or as inhibitors of innate host defense. However, there are few data tha...
Autores principales: | Jinno, Akiko, Hayashida, Atsuko, Jenkinson, Howard F., Park, Pyong Woo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733941/ https://www.ncbi.nlm.nih.gov/pubmed/33293379 http://dx.doi.org/10.1128/mBio.01907-20 |
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