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Production of Noncapped Genomic RNAs Is Critical to Sindbis Virus Disease and Pathogenicity
Alphaviruses are positive-sense RNA viruses that utilize a 5′ cap structure to facilitate translation of viral proteins and to protect the viral RNA genome. Nonetheless, significant quantities of viral genomic RNAs that lack a canonical 5′ cap structure are produced during alphaviral replication and...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Microbiology
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733944/ https://www.ncbi.nlm.nih.gov/pubmed/33262258 http://dx.doi.org/10.1128/mBio.02675-20 |