The Host Cell Metabolite Inositol Hexakisphosphate Promotes Efficient Endogenous HIV-1 Reverse Transcription by Stabilizing the Viral Capsid

A defining activity of retroviruses is reverse transcription, the process by which the viral genomic RNA is converted into the double-stranded DNA required for virus replication. Reverse transcriptase (RT), the viral enzyme responsible for this process, was identified in 1970 by assaying permeabiliz...

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Detalles Bibliográficos
Autores principales: Jennings, Jordan, Shi, Jiong, Varadarajan, Janani, Jamieson, Parker J., Aiken, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733946/
https://www.ncbi.nlm.nih.gov/pubmed/33262260
http://dx.doi.org/10.1128/mBio.02820-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733946/
https://www.ncbi.nlm.nih.gov/pubmed/33262260
http://dx.doi.org/10.1128/mBio.02820-20

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