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Comprehensive Genomic Investigation of Adaptive Mutations Driving the Low-Level Oxacillin Resistance Phenotype in Staphylococcus aureus

Antistaphylococcal penicillins such as oxacillin are the key antibiotics in the treatment of invasive methicillin-susceptible Staphylococcus aureus (MSSA) infections; however, mec gene-independent resistance adaptation can cause treatment failure. Despite its clinical relevance, the basis of this ph...

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Detalles Bibliográficos
Autores principales: Giulieri, Stefano G., Guérillot, Romain, Kwong, Jason C., Monk, Ian R., Hayes, Ashleigh S., Daniel, Diane, Baines, Sarah, Sherry, Norelle L., Holmes, Natasha E., Ward, Peter, Gao, Wei, Seemann, Torsten, Stinear, Timothy P., Howden, Benjamin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733948/
https://www.ncbi.nlm.nih.gov/pubmed/33293382
http://dx.doi.org/10.1128/mBio.02882-20