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Mechanistic Model of Signaling Dynamics Across an Epithelial Mesenchymal Transition

Intracellular signaling pathways are at the core of cellular information processing. The states of these pathways and their inputs determine signaling dynamics and drive cell function. Within a cancerous tumor, many combinations of cell states and microenvironments can lead to dramatic variations in...

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Detalles Bibliográficos
Autores principales: Wade, James D., Lun, Xiao-Kang, Zivanovic, Nevena, Voit, Eberhard O., Bodenmiller, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733964/
https://www.ncbi.nlm.nih.gov/pubmed/33329028
http://dx.doi.org/10.3389/fphys.2020.579117