Docking Characterization and in vitro Inhibitory Activity of Flavan-3-ols and Dimeric Proanthocyanidins Against the Main Protease Activity of SARS-Cov-2

We report to use the main protease (M(pro)) of SARS-Cov-2 to screen plant flavan-3-ols and proanthocyanidins. Twelve compounds, (–)-afzelechin (AF), (–)-epiafzelechin (EAF), (+)-catechin (CA), (–)-epicatechin (EC), (+)-gallocatechin (GC), (–)-epigallocatechin (EGC), (+)-catechin-3-O-gallate (CAG), (...

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Detalles Bibliográficos
Autores principales: Zhu, Yue, Xie, De-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Plant Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733993/
https://www.ncbi.nlm.nih.gov/pubmed/33329667
http://dx.doi.org/10.3389/fpls.2020.601316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733993/
https://www.ncbi.nlm.nih.gov/pubmed/33329667
http://dx.doi.org/10.3389/fpls.2020.601316

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