Epigenetic inactivation of IRX4 is responsible for acceleration of cell growth in human pancreatic cancer

Epigenetic gene silencing by aberrant DNA methylation is one of the important mechanisms leading to loss of key cellular pathways in tumorigenesis. Methyl‐CpG‐targeted transcriptional activation (MeTA) reactivates hypermethylation‐mediated silenced genes in a different way from DNA‐demethylating age...

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Detalles Bibliográficos
Autores principales: Chakma, Kanchan, Gu, Zhaodi, Abudurexiti, Yakefujiang, Hata, Tatsuo, Motoi, Fuyuhiko, Unno, Michiaki, Horii, Akira, Fukushige, Shinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734003/
https://www.ncbi.nlm.nih.gov/pubmed/32894817
http://dx.doi.org/10.1111/cas.14644

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734003/
https://www.ncbi.nlm.nih.gov/pubmed/32894817
http://dx.doi.org/10.1111/cas.14644

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