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NH(2)‐terminal fragment of ZF21 protein suppresses tumor invasion via inhibiting the interaction of ZF21 with FAK

Cellular migration, coupled with the degradation of the extracellular matrix (ECM), is a key step in tumor invasion and represents a promising therapeutic target in malignant tumors. Focal adhesions (FAs) and invadopodia, which are distinct actin‐based cellular structures, play key roles in cellular...

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Detalles Bibliográficos
Autores principales: Nagano, Makoto, Hoshino, Daisuke, Toshima, Jiro, Seiki, Motoharu, Koshikawa, Naohiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734166/
https://www.ncbi.nlm.nih.gov/pubmed/32976654
http://dx.doi.org/10.1111/cas.14665