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Small subset of Wnt‐activated cells is an initiator of regrowth in colorectal cancer organoids after irradiation

Most colorectal cancers (CRCs) are differentiated adenocarcinomas, which maintain expression of both stemness and differentiation markers. This observation suggests that CRC cells could retain a regeneration system of normal cells upon injury. However, the role of stemness in cancer cell regeneratio...

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Detalles Bibliográficos
Autores principales: Endo, Hiroko, Kondo, Jumpei, Onuma, Kunishige, Ohue, Masayuki, Inoue, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734167/
https://www.ncbi.nlm.nih.gov/pubmed/33043499
http://dx.doi.org/10.1111/cas.14683