Cargando…

Collective cancer cell invasion in contact with fibroblasts through integrin‐α5β1/fibronectin interaction in collagen matrix

Interaction of cancer cells with cancer‐associated fibroblasts (CAFs) plays critical roles in tumor progression. Recently we proposed a new tumor invasion mechanism in which invasive cancer cells individually migrate on elongate protrusions of CAFs (CAF fibers) in 3‐D collagen matrix. In this mechan...

Descripción completa

Detalles Bibliográficos
Autores principales: Miyazaki, Kaoru, Togo, Shinsaku, Okamoto, Reiko, Idiris, Alimjan, Kumagai, Hiromichi, Miyagi, Yohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734169/
https://www.ncbi.nlm.nih.gov/pubmed/32979884
http://dx.doi.org/10.1111/cas.14664