Permeation mechanisms through the selectivity filter and the open helix bundle crossing gate of GIRK2

G protein-gated inwardly rectifying potassium channels (GIRK) are essential for the regulation of cellular excitability, a physiological function that relies critically on the conduction of K(+) ions, which is dependent on two molecular mechanisms, namely selectivity and gating. Molecular Dynamics (...

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Detalles Bibliográficos
Autores principales: Li, Dai-Lin, Hu, Liang, Wang, Lei, Chen, Chin-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734222/
https://www.ncbi.nlm.nih.gov/pubmed/33335691
http://dx.doi.org/10.1016/j.csbj.2020.11.039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734222/
https://www.ncbi.nlm.nih.gov/pubmed/33335691
http://dx.doi.org/10.1016/j.csbj.2020.11.039

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