Genetic perturbation of IFN-α transcriptional modulators in human endothelial cells uncovers pivotal regulators of angiogenesis

Interferon-α (IFN-α) comprises a family of 13 cytokines involved in the modulation of antiviral, immune, and anticancer responses by orchestrating a complex transcriptional network. The activation of IFN-α signaling pathway in endothelial cells results in decreased proliferation and migration, ultim...

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Detalles Bibliográficos
Autores principales: Ciccarese, Francesco, Grassi, Angela, Pasqualini, Lorenza, Rosano, Stefania, Noghero, Alessio, Montenegro, Francesca, Bussolino, Federico, Di Camillo, Barbara, Finesso, Lorenzo, Toffolo, Gianna Maria, Mitola, Stefania, Indraccolo, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734228/
https://www.ncbi.nlm.nih.gov/pubmed/33335694
http://dx.doi.org/10.1016/j.csbj.2020.11.048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734228/
https://www.ncbi.nlm.nih.gov/pubmed/33335694
http://dx.doi.org/10.1016/j.csbj.2020.11.048

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