Functionalized Oxoindolin Hydrazine Carbothioamide Derivatives as Highly Potent Inhibitors of Nucleoside Triphosphate Diphosphohydrolases

Ectonucleoside triphosphate diphosphohydrolases (NTPDases) are ectoenzymes that play an important role in the hydrolysis of nucleoside triphosphate and diphosphate to nucleoside monophosphate. NTPDase1, -2, -3 and -8 are the membrane bound members of this enzyme family that are responsible for regul...

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Detalles Bibliográficos
Autores principales: Afzal, Saira, al-Rashida, Mariya, Hameed, Abdul, Pelletier, Julie, Sévigny, Jean, Iqbal, Jamshed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734281/
https://www.ncbi.nlm.nih.gov/pubmed/33328992
http://dx.doi.org/10.3389/fphar.2020.585876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734281/
https://www.ncbi.nlm.nih.gov/pubmed/33328992
http://dx.doi.org/10.3389/fphar.2020.585876

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