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Enhanced Fatty Acid Synthesis Leads to Subset Imbalance and IFN-γ Overproduction in T Helper 1 Cells
Recent reports have shown the importance of IFN-γ and T-bet(+) B cells in the pathology of SLE, suggesting the involvement of IFN-γ-producing T-bet(+) CD4(+) cells, i.e., Th1 cells. This study determined the changes in Th1 subsets with metabolic shift and their potential as therapeutic targets in SL...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734283/ https://www.ncbi.nlm.nih.gov/pubmed/33329581 http://dx.doi.org/10.3389/fimmu.2020.593103 |