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Linagliptin Regulates the Mitochondrial Respiratory Reserve to Alter Platelet Activation and Arterial Thrombosis

Background: The pharmacological inhibition of dipeptidyl peptidase-4 (DPP-4) potentiates incretin action, and DPP-4 is a drug target for type 2 diabetes and reducing cardiovascular risk. However, little is known about the non-enteroendocrine pathways by which DPP-4 might contribute to ischaemic card...

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Detalles Bibliográficos
Autores principales: Li, Yi, Li, Rong, Feng, Ziqian, Wan, Qin, Wu, Jianbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734318/
https://www.ncbi.nlm.nih.gov/pubmed/33328991
http://dx.doi.org/10.3389/fphar.2020.585612