NTRK Fusions and TRK Inhibitors: Potential Targeted Therapies for Adult Glioblastoma

INTRODUCTION: Glioblastoma multiforme (GBM) is the most common primary central nervous (CNS) system malignancy with a poor prognosis. The standard treatment for GBM is neurosurgical resection, followed by radiochemotherapy and adjuvant temozolomide chemotherapy. Predictive biomarkers, such as methyl...

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Detalles Bibliográficos
Autores principales: Wang, Yuekun, Long, Piaopiao, Wang, Yu, Ma, Wenbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734330/
https://www.ncbi.nlm.nih.gov/pubmed/33330081
http://dx.doi.org/10.3389/fonc.2020.593578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734330/
https://www.ncbi.nlm.nih.gov/pubmed/33330081
http://dx.doi.org/10.3389/fonc.2020.593578

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