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NTRK Fusions and TRK Inhibitors: Potential Targeted Therapies for Adult Glioblastoma
INTRODUCTION: Glioblastoma multiforme (GBM) is the most common primary central nervous (CNS) system malignancy with a poor prognosis. The standard treatment for GBM is neurosurgical resection, followed by radiochemotherapy and adjuvant temozolomide chemotherapy. Predictive biomarkers, such as methyl...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734330/ https://www.ncbi.nlm.nih.gov/pubmed/33330081 http://dx.doi.org/10.3389/fonc.2020.593578 |