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Viral RNA load in plasma is associated with critical illness and a dysregulated host response in COVID-19

BACKGROUND: COVID-19 can course with respiratory and extrapulmonary disease. SARS-CoV-2 RNA is detected in respiratory samples but also in blood, stool and urine. Severe COVID-19 is characterized by a dysregulated host response to this virus. We studied whether viral RNAemia or viral RNA load in pla...

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Detalles Bibliográficos
Autores principales: Bermejo-Martin, Jesús F., González-Rivera, Milagros, Almansa, Raquel, Micheloud, Dariela, Tedim, Ana P., Domínguez-Gil, Marta, Resino, Salvador, Martín-Fernández, Marta, Ryan Murua, Pablo, Pérez-García, Felipe, Tamayo, Luis, Lopez-Izquierdo, Raúl, Bustamante, Elena, Aldecoa, César, Gómez, José Manuel, Rico-Feijoo, Jesús, Orduña, Antonio, Méndez, Raúl, Fernández Natal, Isabel, Megías, Gregoria, González-Estecha, Montserrat, Carriedo, Demetrio, Doncel, Cristina, Jorge, Noelia, Ortega, Alicia, de la Fuente, Amanda, del Campo, Félix, Fernández-Ratero, José Antonio, Trapiello, Wysali, González-Jiménez, Paula, Ruiz, Guadalupe, Kelvin, Alyson A., Ostadgavahi, Ali Toloue, Oneizat, Ruth, Ruiz, Luz María, Miguéns, Iria, Gargallo, Esther, Muñoz, Ioana, Pelegrin, Sara, Martín, Silvia, García Olivares, Pablo, Cedeño, Jamil Antonio, Ruiz Albi, Tomás, Puertas, Carolina, Berezo, Jose Ángel, Renedo, Gloria, Herrán, Rubén, Bustamante-Munguira, Juan, Enríquez, Pedro, Cicuendez, Ramón, Blanco, Jesús, Abadia, Jesica, Gómez Barquero, Julia, Mamolar, Nuria, Blanca-López, Natalia, Valdivia, Luis Jorge, Fernández Caso, Belén, Mantecón, María Ángeles, Motos, Anna, Fernandez-Barat, Laia, Ferrer, Ricard, Barbé, Ferrán, Torres, Antoni, Menéndez, Rosario, Eiros, José María, Kelvin, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734467/
https://www.ncbi.nlm.nih.gov/pubmed/33317616
http://dx.doi.org/10.1186/s13054-020-03398-0