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Periostin Secreted by Carcinoma-Associated Fibroblasts Promotes Ovarian Cancer Cell Platinum Resistance Through the PI3K/Akt Signaling Pathway

Periostin (POSTN) is a protein secreted by mesenchymal cells. Periostin is upregulated in several cancer types and overexpression is associated with poor prognosis. However, the functional role and molecular underpinnings of periostin in epithelial ovarian cancer (EOC) is unknown. In the present stu...

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Detalles Bibliográficos
Autores principales: Chu, Lei, Wang, Fangce, Zhang, Wenjun, Li, Huai-fang, Xu, Jun, Tong, Xiao-wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734496/
https://www.ncbi.nlm.nih.gov/pubmed/33302812
http://dx.doi.org/10.1177/1533033820977535