Photoswitchable Azo- and Diazocine-Functionalized Derivatives of the VEGFR-2 Inhibitor Axitinib

In this study, we aimed at the application of the concept of photopharmacology to the approved vascular endothelial growth factor receptor (VEGFR)-2 kinase inhibitor axitinib. In a previous study, we found out that the photoisomerization of axitinib’s stilbene-like double bond is unidirectional in a...

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Detalles Bibliográficos
Autores principales: Heintze, Linda, Schmidt, Dorian, Rodat, Theo, Witt, Lydia, Ewert, Julia, Kriegs, Malte, Herges, Rainer, Peifer, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734574/
https://www.ncbi.nlm.nih.gov/pubmed/33255816
http://dx.doi.org/10.3390/ijms21238961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734574/
https://www.ncbi.nlm.nih.gov/pubmed/33255816
http://dx.doi.org/10.3390/ijms21238961

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