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Photoswitchable Azo- and Diazocine-Functionalized Derivatives of the VEGFR-2 Inhibitor Axitinib
In this study, we aimed at the application of the concept of photopharmacology to the approved vascular endothelial growth factor receptor (VEGFR)-2 kinase inhibitor axitinib. In a previous study, we found out that the photoisomerization of axitinib’s stilbene-like double bond is unidirectional in a...
Autores principales: | Heintze, Linda, Schmidt, Dorian, Rodat, Theo, Witt, Lydia, Ewert, Julia, Kriegs, Malte, Herges, Rainer, Peifer, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734574/ https://www.ncbi.nlm.nih.gov/pubmed/33255816 http://dx.doi.org/10.3390/ijms21238961 |
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