Pan-Sigma Receptor Modulator RC-106 Induces Terminal Unfolded Protein Response In In Vitro Pancreatic Cancer Model

Pancreatic cancer (PC) remains one of the most lethal cancers worldwide. Sigma receptors (SRs) have been proposed as cancer therapeutic targets. Their main localization suggests they play a potential role in ER stress and in the triggering of the unfolded protein response (UPR). Here, we investigate...

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Detalles Bibliográficos
Autores principales: Cortesi, Michela, Zamagni, Alice, Pignatta, Sara, Zanoni, Michele, Arienti, Chiara, Rossi, Daniela, Collina, Simona, Tesei, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734580/
https://www.ncbi.nlm.nih.gov/pubmed/33260926
http://dx.doi.org/10.3390/ijms21239012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734580/
https://www.ncbi.nlm.nih.gov/pubmed/33260926
http://dx.doi.org/10.3390/ijms21239012

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