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Identification of a Selective RelA Inhibitor Based on DSE-FRET Screening Methods

Nuclear factor-κB (NF-κB) is an important transcription factor involved in various biological functions, including tumorigenesis. Hence, NF-κB has attracted attention as a target factor for cancer treatment, leading to the development of several inhibitors. However, existing NF-κB inhibitors do not...

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Detalles Bibliográficos
Autores principales: Shiroma, Yoshitomo, Fujita, Go, Yamamoto, Takuya, Takahashi, Ryou-u, Kumar, Ashutosh, Zhang, Kam Y. J., Ito, Akihiro, Osada, Hiroyuki, Yoshida, Minoru, Tahara, Hidetoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734590/
https://www.ncbi.nlm.nih.gov/pubmed/33266352
http://dx.doi.org/10.3390/ijms21239150