An incoherent feedforward loop interprets NFκB/RelA dynamics to determine TNF‐induced necroptosis decisions

Balancing cell death is essential to maintain healthy tissue homeostasis and prevent disease. Tumor necrosis factor (TNF) not only activates nuclear factor κB (NFκB), which coordinates the cellular response to inflammation, but may also trigger necroptosis, a pro‐inflammatory form of cell death. Whe...

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Detalles Bibliográficos
Autores principales: Oliver Metzig, Marie, Tang, Ying, Mitchell, Simon, Taylor, Brooks, Foreman, Robert, Wollman, Roy, Hoffmann, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734648/
https://www.ncbi.nlm.nih.gov/pubmed/33314666
http://dx.doi.org/10.15252/msb.20209677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734648/
https://www.ncbi.nlm.nih.gov/pubmed/33314666
http://dx.doi.org/10.15252/msb.20209677

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