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Derivation and utility of an Aβ-PET pathology accumulation index to estimate Aβ load

OBJECTIVE: To evaluate a novel β-amyloid (Aβ)-PET–based quantitative measure (Aβ accumulation index [Aβ index]), including the assessment of its ability to discriminate between participants based on Aβ status using visual read, CSF Aβ(42)/Aβ(40), and post-mortem neuritic plaque burden as standards o...

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Detalles Bibliográficos
Autores principales: Leuzy, Antoine, Lilja, Johan, Buckley, Christopher J., Ossenkoppele, Rik, Palmqvist, Sebastian, Battle, Mark, Farrar, Gill, Thal, Dietmar R., Janelidze, Shorena, Stomrud, Erik, Strandberg, Olof, Smith, Ruben, Hansson, Oskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734735/
https://www.ncbi.nlm.nih.gov/pubmed/33077542
http://dx.doi.org/10.1212/WNL.0000000000011031