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Pharmacokinetic study of a novel oral formulation of S-adenosylmethionine (MSI-195) in healthy subjects: dose escalation, food effect and comparison to a commercial nutritional supplement product

BACKGROUND: A novel, high bioavailability oral, enteric coated tablet formulation of S-adenosylmethionine (MSI-195) has been developed for life science application. The present research reports on a Phase 1 study to (i) determine the safety of single doses of MSI-195 (ii) to determine the dose propo...

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Detalles Bibliográficos
Autores principales: Cameron, Beth R., Ferreira, Ludvina, MacDonald, I. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734772/
https://www.ncbi.nlm.nih.gov/pubmed/33317621
http://dx.doi.org/10.1186/s40360-020-00466-7