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Musashi-1 promotes cancer stem cell properties of glioblastoma cells via upregulation of YTHDF1

BACKGROUND: Glioblastoma (GBM) is the most lethal brain tumor characterized by high morbidity and limited treatment options. Tumor malignancy is usually associated with the epigenetic marks, which coordinate gene expression to ascertain relevant phenotypes. One of such marks is m6A modification of R...

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Detalles Bibliográficos
Autores principales: Yarmishyn, Aliaksandr A., Yang, Yi-Ping, Lu, Kai-Hsi, Chen, Yi-Chen, Chien, Yueh, Chou, Shih-Jie, Tsai, Ping-Hsing, Ma, Hsin-I., Chien, Chian-Shiu, Chen, Ming-Teh, Wang, Mong-Lien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734781/
https://www.ncbi.nlm.nih.gov/pubmed/33317545
http://dx.doi.org/10.1186/s12935-020-01696-9