Extracellular signal-regulated kinase 1/2 is required for complement component C1q and fibronectin dependent enhancement of Fcγ- receptor mediated phagocytosis in mouse and human cells

BACKGROUND: C1q is a soluble pattern recognition protein that regulates multiple leukocyte functions, and deficiency in C1q results in autoimmunity. C1q stimulates enhanced phagocytic function through multiple mechanisms including the rapid enhancement of Fcγ receptor (FcγR) -mediated phagocytosis....

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Detalles Bibliográficos
Autores principales: Willmann, Emily A., Pandurovic, Vesna, Jokinen, Anna, Beckley, Danielle, Bohlson, Suzanne S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734837/
https://www.ncbi.nlm.nih.gov/pubmed/33317446
http://dx.doi.org/10.1186/s12865-020-00393-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734837/
https://www.ncbi.nlm.nih.gov/pubmed/33317446
http://dx.doi.org/10.1186/s12865-020-00393-6

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