Human multipotent mesenchymal stromal cells cytokine priming promotes RAB27B-regulated secretion of small extracellular vesicles with immunomodulatory cargo

BACKGROUND: The paracrine effects of multipotent mesenchymal stromal cells (MSCs) are mediated by their secretome composed by soluble factors (i.e., cytokines, growth factors, hormones) and extracellular vesicles (EVs). EVs promote intercellular communication, and the EV cargoes [e.g., proteins, sol...

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Detalles Bibliográficos
Autores principales: Cheng, Anastasia, Choi, Dongsic, Lora, Maximilien, Shum-Tim, Dominique, Rak, Janusz, Colmegna, Inés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734842/
https://www.ncbi.nlm.nih.gov/pubmed/33317598
http://dx.doi.org/10.1186/s13287-020-02050-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734842/
https://www.ncbi.nlm.nih.gov/pubmed/33317598
http://dx.doi.org/10.1186/s13287-020-02050-6

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