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ELABELA ameliorates hypoxic/ischemic-induced bone mesenchymal stem cell apoptosis via alleviation of mitochondrial dysfunction and activation of PI3K/AKT and ERK1/2 pathways

BACKGROUND: Mesenchymal stem cells (MSCs) have exerted their brilliant potential to promote heart repair following myocardial infarction. However, low survival rate of MSCs after transplantation due to harsh conditions with hypoxic and ischemic stress limits their therapeutic efficiency in treating...

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Detalles Bibliográficos
Autores principales: Fu, Jiaying, Chen, Xuxiang, Liu, Xin, Xu, Daishi, Yang, Huan, Zeng, Chaotao, Long, Huibao, Zhou, Changqing, Wu, Haidong, Zheng, Guanghui, Wu, Hao, Wang, Wuming, Wang, Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734864/
https://www.ncbi.nlm.nih.gov/pubmed/33317626
http://dx.doi.org/10.1186/s13287-020-02063-1