XRCC4 rs28360071 intronic variant is associated with increased risk for infant acute lymphoblastic leukemia with KMT2A rearrangements

Early age acute leukemia (EAL) shows a high frequency of KMT2A-rearrangements (KMT2A-r). Previous investigations highlighted double-strand breaks arising from maternal exposure to xenobiotics during pregnancy as a risk factor for EAL and KMT2A-r. In this case-control study, we investigated the relat...

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Detalles Bibliográficos
Autores principales: Louzada-Neto, Orlando, Lopes, Bruno A., Brisson, Gisele D., Andrade, Francianne G., Cezar, Ingrid S., Santos-Rebouças, Cíntia B., Albano, Rodolpho M., Pombo-de-Oliveira, Maria S., Rossini, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2020
Materias:
Human and Medical Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734917/
https://www.ncbi.nlm.nih.gov/pubmed/33270074
http://dx.doi.org/10.1590/1678-4685-GMB-2020-0160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734917/
https://www.ncbi.nlm.nih.gov/pubmed/33270074
http://dx.doi.org/10.1590/1678-4685-GMB-2020-0160

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