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Disease-Causing Mutations and Rearrangements in Long Non-coding RNA Gene Loci

The classic understanding of molecular disease-mechanisms is largely based on protein-centric models. During the past decade however, genetic studies have identified numerous disease-loci in the human genome that do not encode proteins. Such non-coding DNA variants increasingly gain attention in dia...

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Detalles Bibliográficos
Autores principales: Aznaourova, Marina, Schmerer, Nils, Schmeck, Bernd, Schulte, Leon N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735109/
https://www.ncbi.nlm.nih.gov/pubmed/33329688
http://dx.doi.org/10.3389/fgene.2020.527484