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Galectin-9 expression defines exhausted T cells and impaired cytotoxic NK cells in patients with virus-associated solid tumors
BACKGROUND: We have previously reported that the upregulation of galectin-9 (Gal-9) on CD4(+) and CD8(+) T cells in HIV patients was associated with impaired T cell effector functions. Gal-9 is a ligand for T cell immunoglobulin and mucin domain-3, and its expression on T cells in cancer has not bee...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BMJ Publishing Group
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735134/ https://www.ncbi.nlm.nih.gov/pubmed/33310773 http://dx.doi.org/10.1136/jitc-2020-001849 |