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High-resolution analyses of human sperm dynamic methylome reveal thousands of novel age-related epigenetic alterations
BACKGROUND: Children of aged fathers are at a higher risk of developing mental disorders. Alterations in sperm DNA methylation have been implicated as a potential cause. However, age-dependent modifications of the germ cells’ epigenome remain poorly understood. Our objective was to assess the DNA me...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735420/ https://www.ncbi.nlm.nih.gov/pubmed/33317634 http://dx.doi.org/10.1186/s13148-020-00988-1 |