Mitochondrial dysfunction induces RNA interference in C. elegans through a pathway homologous to the mammalian RIG-I antiviral response

RNA interference (RNAi) is an antiviral pathway common to many eukaryotes that detects and cleaves foreign nucleic acids. In mammals, mitochondrially localized proteins such as mitochondrial antiviral signaling (MAVS), retinoic acid-inducible gene I (RIG-I), and melanoma differentiation-associated p...

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Detalles Bibliográficos
Autores principales: Mao, Kai, Breen, Peter, Ruvkun, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735679/
https://www.ncbi.nlm.nih.gov/pubmed/33264285
http://dx.doi.org/10.1371/journal.pbio.3000996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735679/
https://www.ncbi.nlm.nih.gov/pubmed/33264285
http://dx.doi.org/10.1371/journal.pbio.3000996

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